SCOT

SCOT (Strong Conservation of Theme) is a concept in systems biology and network analysis that suggests certain functional modules or themes tend to be preserved across different organisms or conditions. It highlights that specific patterns or interactions within biological systems remain consistent over time or evolutionary distances, indicating their fundamental importance. This conservation helps researchers understand core biological processes, identify universal targets for research or therapy, and decipher how complex biological functions are maintained amidst variability. Essentially, SCOT emphasizes the stability of key functional components within the dynamic complexity of living systems.