Scleroderma (genus)

Scleroderma is a group of autoimmune diseases characterized by the hardening and tightening of the skin and connective tissues due to excess collagen production. The term "genus" indicates it includes multiple related conditions. These diseases can also affect internal organs, leading to symptoms like difficulty swallowing, lung issues, or kidney problems. Scleroderma involves immune system dysfunction, causing inflammation and abnormal tissue repair. Its exact cause is unknown, but it involves genetic and environmental factors. Diagnosis and management focus on symptom relief and preventing organ damage, often requiring a multidisciplinary medical approach.