Satellite cell niche

The satellite cell niche is the specialized environment surrounding muscle stem cells (satellite cells) within muscle tissue. This niche includes nearby cells, blood vessels, extracellular matrix, and signaling molecules that collectively regulate satellite cell activity. It maintains these stem cells in a reserve state, supports their activation for muscle repair, and ensures proper regeneration after injury. Essentially, the niche provides the essential biological conditions and signals that keep satellite cells ready to respond and help repair damaged muscle, maintaining muscle health and strength throughout life.