RYR2 (Ryanodine Receptor 2)

RYR2 (Ryanodine Receptor 2) is a protein found in heart muscle cells that acts as a channel on the cell's internal calcium storage, called the sarcoplasmic reticulum. It regulates the release of calcium ions, which are essential for triggering heart muscle contractions. Proper functioning of RYR2 ensures the heart beats effectively, while mutations or malfunctions can disrupt calcium flow, leading to irregular heart rhythms or conditions like arrhythmia. In summary, RYR2 is vital for coordinating the electrical and mechanical activities that allow the heart to pump blood efficiently.