RPN1 (Regulatory Particle Non-ATPase 1)

RPN1, or Regulatory Particle Non-ATPase 1, is a component of the proteasome, a complex responsible for degrading unneeded or damaged proteins in cells. RPN1 is part of the regulatory particle that recognizes, unfolds, and prepares proteins for breakdown. Unlike some parts of the proteasome that use energy (ATP) to drive these processes, RPN1 plays a structural and scaffolding role, aiding in substrate recognition and interaction with other regulatory molecules. Its function is essential for maintaining cellular protein quality control and overall cell health.