Richters transformation

Richter’s transformation is a medical process where certain blood cancers, like chronic lymphocytic leukemia (CLL), change into a more aggressive type of lymphoma called diffuse large B-cell lymphoma. This transformation often leads to a faster-growing, more serious illness that requires different, more intensive treatment. It occurs because the cancer cells undergo genetic changes, making them more aggressive. Detecting Richter’s transformation is important for adjusting treatment plans and improving patient outcomes.