Rheumatoid Arthritis Pathogenesis

Rheumatoid arthritis (RA) is an autoimmune disease where the body mistakenly attacks its own joint tissues. This attack is driven by immune cells that infiltrate the joints, leading to inflammation, pain, and swelling. Over time, the persistent inflammation can damage cartilage and bone, affecting joint function. Genetic factors and environmental triggers, such as infections, may contribute to the onset of RA, making the immune system overactive. The resulting inflammation can also affect other body systems, highlighting the disease's complexity beyond just joint issues. Proper management is key to improving quality of life and minimizing damage.