Retinoblastoma Pathology

Retinoblastoma is a rare eye cancer that primarily affects children, usually before the age of 5. It originates in the retina, the light-sensitive tissue at the back of the eye. The condition arises from mutations in the RB1 gene, which normally helps control cell growth and prevents tumors. In retinoblastoma, these mutations can lead to uncontrolled cell division, forming a tumor. Symptoms may include a white reflection in the eye, crossed eyes, or vision problems. Early detection and treatment are crucial for preserving vision and improving survival rates.