Rb gene

The Rb gene produces a protein called pRb that helps regulate cell growth and division, acting as a tumor suppressor. It controls how and when cells divide, preventing them from growing uncontrollably. When the Rb gene is functioning properly, it keeps cell growth in check. However, if the Rb gene is mutated or lost, this control is disrupted, increasing the risk of cells becoming cancerous. Mutations in the Rb gene are linked to certain cancers, most notably retinoblastoma, a rare eye cancer in children. Overall, the Rb gene plays a crucial role in maintaining healthy cell growth and preventing cancer.