RAS mutation

RAS mutations involve changes in specific genes (like KRAS, NRAS, or HRAS) that code for proteins responsible for transmitting signals within cells. These signals help control cell growth, division, and survival. When mutated, RAS genes can become permanently active, leading cells to grow uncontrollably and evade normal regulatory mechanisms. This abnormal activity is common in many cancers, making RAS mutations important targets for research and potential therapies. Essentially, a RAS mutation disrupts the normal balance of cell growth signals, contributing to the development and progression of tumors.