Randle Cycle

The Randle Cycle, also known as the glucose-fatty acid cycle, describes how the body uses different energy sources. When glucose and fatty acids are both available, the body tends to favor glucose for energy. This occurs because glucose is easier to metabolize. High levels of fatty acids can inhibit glucose utilization, potentially leading to insulin resistance. Understanding this cycle helps explain why diet and energy sources impact metabolism, exercise performance, and conditions like obesity and diabetes. Essentially, the Randle Cycle highlights how our bodies prioritize energy sources to maintain balance and efficiency.