Purine nucleoside phosphorylase

Purine nucleoside phosphorylase (PNP) is an enzyme that plays a crucial role in the recycling and breakdown of purines, which are fundamental components of DNA and RNA. It works by removing specific parts from purine nucleosides (molecules made of a purine base and sugar), converting them into purine bases and ribose sugars. This process helps the body regulate purine levels, prevent toxic buildup, and obtain energy. PNP activity is especially important in immune cells, and deficiencies can lead to immune system disorders. Overall, PNP is essential for maintaining nucleotide balance and proper cell function.