Psychophysiological Interaction

Psychophysiological Interaction (PPI) is a method used in brain imaging studies to explore how different brain regions communicate with each other during specific mental tasks or states. It examines whether the connection between two areas becomes stronger or weaker depending on what someone is doing or thinking. For example, PPI can reveal if the link between memory and emotion centers increases when recalling a happy memory. This helps researchers understand how the brain’s network dynamics change based on activity or context, shedding light on the flexible nature of neural communication in various mental processes.