PSEN1 (Presenilin 1)

PSEN1 (Presenilin 1) is a gene that produces a protein crucial for the functioning of a complex involved in processing other proteins within nerve cells. This processing is essential for maintaining healthy brain activity. Mutations or changes in the PSEN1 gene can lead to improper protein processing, which is linked to early-onset Alzheimer's disease, a form of dementia that begins at a younger age. Essentially, PSEN1 plays a key role in brain health, and problems with this gene can contribute to the development of neurodegenerative changes associated with Alzheimer's.