Image for PrPC (normal cellular prion protein)

PrPC (normal cellular prion protein)

PrPC, or normal cellular prion protein, is a naturally occurring protein found mainly in the brain and nervous system. Its exact function isn’t fully understood, but it is believed to play roles in protecting cells, supporting communication between neurons, and possibly managing metal ions like copper. PrPC is structured in a way that keeps it stable and functional under normal conditions. Importantly, it is distinct from the prions that cause diseases; when PrPC changes shape into a misfolded form, it can lead to harmful brain conditions. Under healthy circumstances, PrPC is essential for proper neural function.