PrP^C

PrP^C, or cellular prion protein, is a normal protein found mainly in the nervous system. It helps support brain cell functions and may be involved in protecting cells from damage. Under normal conditions, it exists in a healthy, folded state. However, in certain circumstances, it can misfold into a disease-causing form called PrP^Sc, which can clump together and lead to neurodegenerative diseases like Creutzfeldt-Jakob disease. Understanding PrP^C is important for researching these serious brain disorders and developing potential treatments.