Protein-Ligand Interaction

Protein-ligand interactions occur when a molecule (the ligand) binds to a specific site on a protein, similar to a key fitting into a lock. These interactions are crucial for biological processes like signaling or enzyme activity. The ligand’s shape, charge, and chemical properties determine how well it fits and binds to the protein. This binding can activate or inhibit the protein’s function, influencing biological responses. Understanding these interactions helps in drug development, as medications are designed to target specific proteins by mimicking or blocking natural ligands.