Protein homeostasis

Protein homeostasis, or proteostasis, is the process by which cells maintain the proper balance, quantity, and quality of proteins. Proteins are essential for cell function, and their production, folding, and degradation are tightly regulated to prevent issues like misfolded proteins or shortages. This involves various mechanisms, including synthesis by ribosomes, proper folding assisted by chaperones, and removal of damaged or excess proteins through degradation pathways. Maintaining proteostasis ensures cells operate efficiently and adapt to changes, preventing diseases linked to protein mismanagement, such as neurodegenerative disorders.