Procainamide-induced Lupus

Procainamide-induced lupus is a condition that can occur in some patients taking the medication procainamide, which is used to treat irregular heart rhythms. In rare cases, this drug can trigger an autoimmune response similar to systemic lupus erythematosus (SLE), a chronic illness where the immune system mistakenly attacks healthy tissues. Symptoms may include joint pain, skin rashes, and fatigue. Importantly, this form of lupus typically resolves once the medication is discontinued, making it distinct from chronic lupus, which persists independently of any medication. Regular monitoring and communication with a healthcare provider are essential for managing potential side effects.