Prion-like Mechanisms

Prion-like mechanisms involve certain proteins that can change shape and then induce healthy versions of themselves to do the same. These misfolded proteins stick together, forming aggregates that can disrupt cell function. Similar to infectious prions causing disease, prion-like proteins can spread this harmful misfolding within the brain, contributing to neurodegenerative conditions like Alzheimer's and Parkinson's. This process can propagate from cell to cell, leading to progressive damage. Understanding these mechanisms helps scientists investigate why these diseases develop and how to potentially prevent or treat them.