Primary progressive Multiple Sclerosis

Primary progressive multiple sclerosis (PPMS) is a form of multiple sclerosis characterized by a gradual and steady worsening of neurological function from the onset, without periods of remission. It involves the immune system attacking the protective covering of nerve fibers in the central nervous system, leading to progressive physical and cognitive symptoms such as weakness, difficulty walking, and coordination problems. Unlike other MS types, PPMS does not typically have distinct relapses or remissions, making progression more continuous. Its exact cause is unknown, but it involves a combination of genetic and environmental factors. Treatment aims to manage symptoms and slow progression.