Primary Myelofibrosis

Primary myelofibrosis is a rare blood disorder where the bone marrow's ability to produce blood cells becomes impaired due to abnormal cell growth and scarring (fibrosis). This leads to decreased red blood cells (causing anemia), increased abnormal white blood cells, and fewer healthy platelets, resulting in symptoms like fatigue, weakness, easy bruising, and an enlarged spleen. The condition is caused by genetic mutations affecting blood cell production. It can progress over time, and while there is no cure, treatments aim to manage symptoms, reduce complications, and improve quality of life.