Post-transplant lymphoproliferative disorder (PTLD)

Post-transplant lymphoproliferative disorder (PTLD) is a condition that can occur after an organ transplant, where some immune cells (lymphocytes) grow uncontrollably. It usually happens because immunosuppressive medicines used to prevent rejection weaken the immune system, allowing certain viruses, like Epstein-Barr virus (EBV), to trigger abnormal cell growth. PTLD can range from benign to more aggressive, potentially affecting the transplanted organ and causing symptoms like swelling, fever, or fatigue. Early detection and treatment, often involving reducing immunosuppressants or targeted therapies, are important for managing the condition effectively.