Polycomb Repressive Complex 2 (PRC2)

Polycomb Repressive Complex 2 (PRC2) is a group of proteins that helps regulate gene activity by modifying DNA packaging. It adds chemical tags called methyl groups to a specific histone protein, H3, which condenses the surrounding DNA and prevents certain genes from being turned on. This process is essential for controlling cell development, maintaining cell identity, and silencing genes that shouldn't be active in specific contexts. PRC2 plays a crucial role in development and can be involved in diseases like cancer when its function is disrupted.