Image for Polycomb Repressive Complex 1 (PRC1)

Polycomb Repressive Complex 1 (PRC1)

Polycomb Repressive Complex 1 (PRC1) is a protein group inside cells that helps regulate gene activity by modifying the structure of DNA and its associated proteins called histones. PRC1 specifically adds chemical tags to histones, causing the DNA to become more compact and less accessible, which silences gene expression. This process is crucial for controlling cell development, maintaining cell identity, and preventing unwanted gene activity. PRC1’s activity is vital for normal development and preventing diseases like cancer, as it helps ensure genes are turned on or off at the right times.