plasminogen activator inhibitor-1 (PAI-1)

Plasminogen activator inhibitor-1 (PAI-1) is a protein in the blood that regulates the body’s process of breaking down blood clots. It works by inhibiting substances that dissolve clots, helping to control bleeding and promote healing. However, high levels of PAI-1 can lead to excessive clot formation, increasing the risk of conditions like heart attacks or strokes. PAI-1 is produced by various cells and is involved in balancing clot formation and breakdown, playing a crucial role in maintaining healthy blood flow and wound healing.