Image for plasma membrane calcium ATPase (PMCA)

plasma membrane calcium ATPase (PMCA)

The plasma membrane calcium ATPase (PMCA) is a specialized protein located in the cell’s membrane that helps regulate calcium levels inside the cell. It actively transports calcium ions out of the cell using energy from ATP (a form of cellular fuel). Maintaining proper calcium balance is essential for various cellular functions, including signaling, muscle contractions, and nerve activity. PMCA ensures calcium doesn’t accumulate excessively, which could disrupt normal cell processes. By controlling calcium concentrations, PMCA plays a vital role in maintaining cellular health and proper functioning.