plaque rupture

Plaque rupture refers to the breaking apart of accumulated fatty deposits, known as plaques, within the walls of arteries. These plaques are made up of fats, cholesterol, and other substances. When a plaque ruptures, it exposes its inner contents to the bloodstream, which can trigger a blood clot to form at the site. This clot can block the artery, reducing or stopping blood flow to the heart or brain, potentially leading to a heart attack or stroke. Plaque rupture is a key event in the development of acute cardiovascular events associated with atherosclerosis.