Phosphodiesterase inhibitors

Phosphodiesterase inhibitors are medications that block the action of phosphodiesterase enzymes, which break down certain signaling molecules in the body. By inhibiting these enzymes, the drugs increase levels of these molecules, such as cAMP or cGMP, leading to enhanced signaling. This can improve blood flow, relax muscles, and boost cellular communication. They are commonly used to treat conditions like erectile dysfunction (e.g., sildenafil), pulmonary hypertension, and certain heart conditions. Overall, these inhibitors help regulate specific pathways in the body, leading to desired therapeutic effects.