Phosphodiesterase-5 inhibitors

Phosphodiesterase-5 (PDE5) inhibitors are medications that help improve blood flow to certain areas of the body, primarily the penis. They work by blocking an enzyme called PDE5, which breaks down a chemical called cGMP that relaxes blood vessels. By preventing this breakdown, PDE5 inhibitors promote vasodilation, or vessel widening, making it easier to achieve and maintain an erection. These drugs are commonly prescribed for erectile dysfunction and are generally effective and safe but should be used under medical guidance, especially for individuals with cardiovascular issues or those taking certain other medications.