
Phase II metabolic enzymes
Phase II metabolic enzymes are specialized proteins in the body that help process and eliminate foreign substances like drugs, toxins, and chemicals. After Phase I enzymes modify these substances to make them more water-soluble, Phase II enzymes attach small molecules (like sulfate or glucuronic acid) to the modified compounds. This "conjugation" makes the substances easier to excrete through urine or bile. Essentially, Phase II enzymes act as the body's way of safely neutralizing and removing potentially harmful chemicals, supporting detoxification and maintaining internal balance.