Pharmacokinetics of anesthetics

Pharmacokinetics of anesthetics describes how these drugs are absorbed, distributed, metabolized, and eliminated from the body. After administration, anesthetics quickly enter the bloodstream, reaching the brain to induce anesthesia. They then distribute to other tissues, which helps determine the onset and duration of their effect. The body eventually breaks down (metabolizes) these drugs, primarily in the liver, and eliminates them through urine or breath. Understanding this process helps anesthesiologists control the depth and duration of anesthesia, ensuring patient safety and effective sedation during procedures.