periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome

PFAPA syndrome is a condition primarily affecting children, characterized by recurring episodes of fever, sore throat, mouth ulcers (aphthous stomatitis), and swollen neck lymph nodes (cervical adenitis). These episodes happen regularly, usually every few weeks, and resolve on their own. The exact cause isn’t known, but it’s considered an autoinflammatory disorder, meaning the immune system overreacts without an infection. Between episodes, children are usually healthy. Treatment options can include medications like corticosteroids to reduce symptoms, though many children outgrow the condition over time.