Pediatric Spinal Muscular Atrophy

Pediatric Spinal Muscular Atrophy (SMA) is a genetic condition that causes progressive loss of muscle strength and movement in children. It occurs because of a mutation affecting a protein vital for nerve cells that control muscle activity. Without this protein, nerves deteriorate, leading to muscle weakness and, over time, difficulty with mobility, breathing, and swallowing. The severity varies, with some children experiencing mild symptoms and others facing significant challenges. Advances in treatments have improved outcomes, especially when started early, helping children achieve better quality of life and increased independence.