PDGFR (Platelet-Derived Growth Factor Receptor)

PDGFR, or Platelet-Derived Growth Factor Receptor, is a protein located on the surface of certain cells, including those involved in healing and tissue growth. It functions like a switch that activates when it binds to specific growth factors (PDGFs). Once activated, PDGFR triggers internal signals that promote cell division, movement, and survival. This process is vital for normal tissue repair and development. However, abnormal activation or mutations of PDGFR can contribute to diseases like cancer, where cells grow uncontrollably. Understanding PDGFR is important for developing targeted therapies for such conditions.