PBAF complex

The PBAF complex (Polybromo-associated BAF complex) is a group of proteins that work together to regulate how DNA is packaged in the cell nucleus. By remodeling the structure of chromatin (the combination of DNA and proteins), PBAF can control which genes are turned on or off. This process is essential for cell development, differentiation, and response to signals. PBAF is a specialized form of the SWI/SNF chromatin remodeling complexes, and it plays a crucial role in maintaining normal cell functions and preventing diseases like cancer.