Pauling wedge

The Pauling wedge is a concept in biology that describes how the shape of a molecule, like hemoglobin, influences its ability to bind oxygen. Imagine a molecule that can change shape, opening or closing like a wedge. When it binds to oxygen, it shifts shape, making it easier for more oxygen molecules to attach—a cooperative effect. This shape change acts like a wedge, helping the molecule switch between states more efficiently, which is crucial for rapid oxygen uptake and release in the body.