Pauling's Principle of Specificity

Pauling's Principle of Specificity states that each enzyme or protein interacts with only particular molecules, known as substrates, due to the precise shape and chemical properties of its active site. This means that a specific enzyme is like a lock designed for a specific key, ensuring that biological reactions happen accurately and efficiently. The principle underscores how molecular structure and fit determine biological function, emphasizing the importance of shape and chemical compatibility in biochemical interactions.