Pauling's Hypothesis (Linus Pauling)

Pauling's Hypothesis suggests that the structural stability of biological molecules, like enzymes and proteins, is influenced by the way their atoms share electrons—specifically through strong, stable covalent bonds. He proposed that the precise arrangement and bonding of atoms in these molecules are critical for their function, and that certain patterns of electron sharing contribute to their strength and flexibility. This idea helped explain how complex molecules maintain their shape and stability under varying conditions, emphasizing the fundamental role of atomic and electronic structure in biological activity.