pathology of gout

Gout is a form of inflammatory arthritis caused by the buildup of uric acid crystals in joints. When uric acid levels are elevated, these crystals form and deposit in tissues, triggering the immune system to respond aggressively. This results in intense pain, swelling, redness, and warmth in the affected joint, often the big toe. Over time, repeated attacks can cause joint damage. Gout is linked to factors like diet, genetics, obesity, and other health conditions that affect uric acid metabolism, and managing these factors can help prevent flare-ups.