Pathological angiogenesis

Pathological angiogenesis is the abnormal formation of new blood vessels from existing ones, occurring when this process becomes uncontrolled or excessive. While normal angiogenesis helps wounds heal and supports tissue growth, in disease states like cancer or diabetic retinopathy, it can lead to problematic blood vessel growth. These unusual vessels may be fragile, leak fluids, or supply tumors with nutrients, promoting disease progression. Understanding this abnormal vessel growth is important for developing treatments that can inhibit or normalize blood vessel formation, helping to manage conditions where angiogenesis becomes harmful.