PAF signaling pathway

The Platelet-Activating Factor (PAF) signaling pathway involves a molecule called PAF that helps cells communicate during inflammation, allergy responses, and other immune functions. PAF binds to specific receptors on cell surfaces, triggering a cascade of chemical signals inside the cell. These signals can promote blood vessel dilation, increase blood vessel permeability (allowing immune cells to reach tissues), and activate immune cells like leukocytes. This coordinated response helps the body defend against injury or infection but can also contribute to allergic reactions and inflammatory diseases when uncontrolled.