p62/SQSTM1 (sequestosome 1)

p62, also known as SQSTM1, is a multifunctional protein that plays a key role in cellular waste management, particularly in breaking down damaged or unnecessary proteins through a process called autophagy. It acts as an adaptor, recognizing faulty proteins and helping transport them to lysosomes for degradation. p62 also participates in signaling pathways related to cell growth, stress responses, and inflammation. Proper functioning of p62 is vital for maintaining cell health, and its dysfunction has been linked to diseases such as cancer, neurodegenerative disorders, and chronic inflammation.