p53 mutation

A p53 mutation involves a change in the gene that produces the p53 protein, which is crucial for preventing cancer by controlling cell growth and repairing damage. When this gene is mutated, the p53 protein may lose its ability to regulate cells properly, allowing damaged cells to divide uncontrollably. This unchecked growth can lead to tumor development. Such mutations are common in many types of cancer and are considered a key factor in the progression of the disease, making p53 a significant focus in cancer research and potential treatments.