opioid metabolism

Opioid metabolism involves how the body processes these drugs after they are absorbed. Once taken, opioids are mainly broken down in the liver by enzymes into simpler compounds called metabolites. These metabolites are then eliminated from the body through urine or, less often, feces. The efficiency of this process varies among individuals due to genetics, age, health, and other medications, affecting how quickly opioids act and how long their effects last. Proper metabolism is crucial for pain relief and minimizing side effects; understanding it helps in safely managing opioid use.