OAT4 (SLC22A11)

OAT4 (SLC22A11) is a protein that functions as a transporter in the kidneys, helping to move organic anions, such as certain drugs and waste products, from the blood into urine for excretion. It plays a key role in removing toxins and maintaining chemical balance in the body. Located mainly in kidney cells, OAT4 works alongside other transporters to facilitate efficient waste elimination, influencing drug effectiveness and clearance. Variations or changes in OAT4 activity can impact how well the body gets rid of certain substances, affecting drug response and overall metabolic health.