Nitrosative stress

Nitrosative stress occurs when the body produces excessive amounts of reactive nitrogen species, such as nitric oxide and peroxynitrite. These molecules can damage cells by modifying proteins, lipids, and DNA, disrupting normal cellular functions. This imbalance often results from inflammation, infections, or environmental factors, leading to tissue damage and contributing to various diseases like neurodegeneration, cardiovascular issues, and chronic inflammation. Essentially, nitrosative stress is a harmful overproduction of certain nitrogen-based chemicals that overwhelms the body's natural defense systems, causing cellular injury and dysfunction.