Nicastrin

Nicastrin is a protein that plays a key role in a group of enzymes called gamma-secretase, which are involved in processing certain proteins within cell membranes. It acts as a part of this complex, helping to recognize and bind specific protein fragments. This process is important for cell communication and signaling. In particular, gamma-secretase and Nicastrin are known for their role in producing amyloid-beta peptides, which are linked to Alzheimer's disease. Understanding Nicastrin’s function helps researchers explore new ways to treat or prevent such neurological conditions.