New Dietary Ingredient Notification

A New Dietary Ingredient (NDI) Notification is a safety review process required by the FDA when a dietary supplement contains an ingredient not sold in the U.S. before October 1994. The manufacturer must submit scientific evidence showing the ingredient is safe for consumption before marketing it. This process helps ensure that new ingredients are evaluated for safety, protecting consumers while allowing innovation in dietary supplements. If the FDA approves the notification, the ingredient can be legally included in products sold to the public.