neuropathological criteria

Neuropathological criteria are specific features or markers observed in brain tissue that help doctors identify and diagnose brain diseases. Using microscopes and special stains, pathologists look for changes such as abnormal protein deposits, cell loss, or structural damage. These criteria ensure accurate diagnosis by providing standardized guidelines, which are essential for understanding disease mechanisms, guiding treatment, and conducting research. Essentially, they are the scientific standards used to confirm diseases like Alzheimer's or Parkinson's through examination of brain tissue after death.